TrueNat Test
01 Oct 2023 2 mins Download PDF
TrueNat Test
- TrueNat is a is a chip-based, battery-operated RT-PCR kit for point-of-care and rapid molecular test for diagnosis of infectious diseases.
- RT-PCR (Reverse Transcriptase- Polymerase Chain Reaction) employs reverse transcription process that converts RNA into DNA molecule before the gene can be captured in the test.
- It was used as a screening test during COVID-19 pandemic, to identify the E-gene in the SARS-CoV-2 virus, the gene that helps the virus build a spherical envelope around it or detect RdRp enzyme.
- It offers advantages such as:
- Portability
- Lower cost compared to traditional RT-PCR tests.
- Quanity of sampkle required for testing is much less.
- the reagents do not require extreme temperatures compared to conventional RT-PCR tests.
- The test was originally developed for Tuberculosis diagnosis and has been incorporated in India's National Tuberculosis Elimination Programme.
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