Yeztugo HIV Injection

In a historic development in the fight against HIV, the United States Food and Drug Administration (US FDA) has approved Yeztugo HIV injection—a revolutionary drug for the long-acting prevention of HIV.

Manufactured by Gilead Sciences, Yeztugo, scientifically known as Lenacapavir injection, is a twice-yearly HIV shot shown to be 99.9% effective in Phase 3 clinical trials.

This update holds immense relevance for SSC and other government exam aspirants under current affairs, science and technology, and health-related awareness.

What is Yeztugo HIV Injection?

Yeztugo HIV injection is the commercial name for Lenacapavir injection, a long-acting HIV prevention drug. What sets it apart is its biannual schedule, making it the first-ever HIV prevention injection taken just twice a year.

Key Features of Yeztugo HIV Injection:

• Type: Injectable antiretroviral drug

• Manufacturer: Gilead Sciences

• Effectiveness: 99.9% in clinical trials

• Schedule: Once every six months

• Use: Prevents HIV infection before exposure

How Does It Work?

• Unlike traditional oral PrEP drugs that require daily intake, Yeztugo HIV injection works by inhibiting the HIV capsid protein, preventing the virus from multiplying.

• This makes Lenacapavir injection one of the most promising tools in the fight against HIV transmission.

The Yeztugo dosage and schedule involve just two subcutaneous injections per year, which significantly increases adherence among high-risk populations.

Clinical Trial Insights

• In large-scale Phase 3 trials, Yeztugo HIV injection demonstrated near-total efficacy, outperforming many existing oral regimens.

• Its strong results have fast-tracked regulatory approvals in various regions.

The US FDA HIV drug Yeztugo has already been lauded as a breakthrough injectable HIV prevention treatment, and its approval has global implications.

Importance of Global Health

• The approval of Yeztugo HIV injection is a vital step in reducing the global HIV burden, especially in countries where daily medication adherence is low.

• Health organizations and NGOs are pushing to introduce this latest HIV prevention medicine in Asia, Africa, and Latin America.

For aspirants preparing for SSC, UPSC, or State PSC exams, this falls under global health and international cooperation in science and medicine.

Comparative Table: Yeztugo vs. Traditional PrEP

What is Lenacapavir Injection?

• Lenacapavir injection is the scientific term for the drug used in Yeztugo HIV injection.

• It is a capsid inhibitor, meaning it blocks a crucial step in the HIV replication cycle, making it harder for the virus to multiply and infect the host.

Yeztugo Dosage and Schedule

This biannual HIV protection shot has simplified HIV prevention strategies globally.

Additional Related Information for Exams

• Yeztugo HIV injection can prevent new infections in high-risk populations.

• It is expected to reduce healthcare costs by minimizing frequent medication.

• Being a long-acting HIV prevention drug, it is particularly useful in remote or under-resourced areas.

• Gilead Yeztugo's HIV drug may receive WHO pre-qualification for wider international adoption.

SSC Exam Takeaways

For SSC or government job aspirants, here are important points to remember:

• Drug Name: Yeztugo

• Generic Name: Lenacapavir

• Type: HIV prevention injection

• Approval Body: US FDA

• Dosage: Twice a year

• Effectiveness: 99.9%

• Relevance: Public health, science, international development

Final Thoughts

The Yeztugo HIV injection marks a significant advancement in global HIV prevention, offering a convenient, long-acting solution with just two doses a year.

With its high effectiveness, simplified dosage schedule, and US FDA approval, Yeztugo sets a new standard for long-term HIV protection.

For SSC aspirants, this development is crucial from both a health and current affairs perspective, reflecting progress in medical innovation and global public health efforts.