It is a sparsely populated geographic region of the easternmost Isthmus of Panama that extends into northwestern Colombia, around the Gulf of Urabá.It forms the physiographic link between Central and South America.

Over 100,000 minors crossed Darien gap in 2023 to reach US.

Features - A hot, humid area typified by tropical rainforests, mangrove swamps, and low mountain ranges with cloud forest vegetation.

• The Pan-American Highway does not traverse Darién, which effectively blocks land transportation between Central and South America.

National Parks - A pair of contiguous parks administer a large part of the region, Darién National Park in Panama and Los Katíos National Park in Colombia.

Darién National Park is a World Heritage Site in Panama.